CGT Analytical Services

Xws li autologous/allogeneic CAR-T hlwb tsom rau CD19, BCMA, thiab lwm yam, suav nrog cov cim tseem ceeb ntawm kev tswj xyuas zoo xws li kev kho cov noob caj noob ces, cov khoom seem seem, thiab kev ruaj ntseg ntawm tes thaum npaj cell;

CAR-NK cov khoom tau hloov kho rau natural killer (NK) cell modification, nrog rau kev sim ua raws li qhov loj me xws li kev ua ntawm tes, qhov tseeb ntawm cov noob, thiab tawm ntawm- cov teebmeem;

Npog iPSC reprogramming kev txheeb xyuas qhov ua tau zoo, kev ntsuas kev ruaj ntseg ntawm caj ces, kev ntsuam xyuas muaj peev xwm sib txawv, thiab kev tswj xyuas zoo ntawm ntau lub hlwb ua haujlwm (xws li cardiomyocytes thiab paj hlwb) txawv ntawm iPSCs;

suav nrog TCR-T cells, mesenchymal stem cells (MSCs), thiab dendritic cells (DCs), catering rau tus kheej tswj kev xav tau ntawm ntau hom cell.

• Lub chaw soj ntsuam xyuas nruj me ntsis ua raws li GMP kev tswj xyuas qhov zoo, thiab cov txheej txheem kev xeem yog traceable thiab verifiable.

• Daim ntawv tshaj tawm kev xeem ua tau raws li cov qauv kev thov ntawm cov koom haum tswj hwm thoob ntiaj teb xws li NMPA, FDA, thiab EMA.

• Nws tuaj yeem kuaj xyuas qhov qis - gene mutations, exogenous pollutants, thiab cellular impurities;

• Rau cov khoom kho cov noob caj noob ces, nws tuaj yeem txheeb xyuas qhov kev kho kom raug thiab tawm ntawm -cov vev xaib, kom ntseeg tau qhov raug thiab kev nyab xeeb ntawm kev kho cov noob.

• High-throughput parallel detection: Ib txhij ua tiav ntau yam kev ntsuas xws li kev txheeb xyuas cov kab ke ntawm cov noob, kev soj ntsuam tus lej, kev qhia cov noob caj noob ces, thiab kev tshuaj ntsuam xyuas cov kab mob microbial, txhim kho kev tswj kom zoo;

• Customized analysis process: Optimize library building and data analysis schemes for different cell therapy products' technical routes (xws li viral vector transduction, electroporation transfection, and gene editing) kom ntseeg tau tias qhov tseeb thiab kev ntseeg siab ntawm cov txiaj ntsig kev xeem.

• Kev ntsuam xyuas kev ua tau zoo ntawm cov noob caj noob ces: Kev ntsuas qhov kev ua tau zoo ntawm kev ntxig thiab kev sib koom ua ke ntawm qhov chaw tsom xam cov hom phiaj xws li CAR noob thiab TCR noob;

• Off-Tim txiaj ntsig tshawb pom: Los ntawm tag nrho- genome sequencing (WGS) los yog lub hom phiaj sequencing, txheeb xyuas kom raug tshem tawm -cov phiaj xwm phiaj xwm ntawm cov cuab yeej kho cov noob xws li CRISPR thiab TALEN, thiab ntsuas cov kev pheej hmoo;

• Kev ntsuam xyuas kev ruaj ntseg ntawm caj ces: Saib xyuas cov lej hloov pauv (CNV), kev hloov pauv ntawm cov qauv (SV), thiab cov noob hloov pauv hauv cov hlwb thaum nyob hauv vitro nthuav dav, cryopreservation thiab thawing, thiab induced sib txawv.

• Kev tshuaj ntsuam xyuas cov kab mob exogenous: Tshawb xyuas cov kab mob microbial xws li kab mob, cov kab mob, mycoplasma, endogenous retroviruses (ERV), thiab cov kab mob vector residues;

• Kev tsom xam cov khoom sib xws: Sib piv cov yam ntxwv ntawm caj ces thiab kev tswj xyuas cov khoom zoo ntawm cov khoom sib txawv ntawm cov khoom sib txawv kom ntseeg tau tias kev ruaj ntseg ntawm cov khoom loj.

• Kev txheeb xyuas ntawm tes: Qhov tseeb thiab qhov tshwj xeeb ntawm lub hauv paus chiv keeb ntawm tes tau lees paub los ntawm STR typing thiab tshwj xeeb genetic marker detection.